Caprylistat is a nutritional antifungal product containing a variety of fatty acids and biotin, effective in the control of Candida Albicans and other yeast or fungal situations. In capsule form, Vinco’s Caprylistat delivers its active ingredients in the upper gastro-intestinal tract and beyond. **Gluten Free**
Serving Size: 1 Capsule,Servings per Container: 120
Amount per Serving %DV Calcium (Propionate, Carbonate) 30 mg 3% Vitamin E (d-Alpha Tocopherol Succinate) 5 IU 16% Biotin 50 mcg 16% Magnesium (Caprylate) 25 mg 6% Potassium (Sorbate) 30 mg <1% Caprylic Acid (Magnesium) 350 mg * Propionic Acid (Calcium) 100 mg * Sorbic Acid (Potassium) 100 mg *
* Daily Value (DV) not established DV is based on a 2,000 calorie diet
Other Ingredients: Cellulose, Magnesium Stearate, Silicon Dioxide, Coconut Powder
• A nutritional antifungal product • Contains fatty acids and biotin • Helps control yeast or fungal infections • Has been shown to have an inhibition action on the growth of yeast and similar pathogenic organisms
Overview Caprylistat is a nutritional antifungal product containing a variety of fatty acids and biotin, effective in the control of Candida Albicans and other yeast or fungal infections. In capsule form, Vinco's Caprylistat delivers its active ingredients in the upper gastro-intestinal tract
Signs & Symptoms Oral Candidiasis (thrush) - 1) Presence of creamy white patches on the tongue and buccal mucosa. 2) Oral mucosa is painful, raw or ulcerated.
Candida Esophagitis - 1) Pain with swallowing. 2) Difficulty swallowing. 3) Feeling of obstruction. 4) Often associated with treatment of malignancies or AIDS. 5) Occasional substernal chest pain. 6) Sometimes no symptoms until obstruction, bleeding or perforation occurs. 7) Barium swallow may reveal characteristic shaggy mucosa. 8) Definitive diagnoses performed with brush biopsy.
Vaginal Candidiasis - 1) Thick, white, curd-like vaginal discharge. 2) Intense vaginal or vulva itching. 3) Possible irritation upon urination. 4) Redness of the vulva. 5) Disseminated Candidiasis.
Three possible scenarios - 1) Acute onset of fever, tachycardia, tachypnea, and occasionally chills and hypotension, resembling bacterial sepsis. 2) Intermittent fevers, with patients feeling ill only when fevers are present. 3) Progressive deterioration with or without fevers.
Other - May occasionally occur as a skin infection (diaper rash in infants), or in men as swelling and redness on the penis andforeskin.
Physiology Candida albicans is found as part of the skin, the female genital tract, and the entire GI tract of humans. its mere presence in a clinical specimen does not necessarily indicate the presence of invasive disease. In a healthy body, C. albicans is controlled by beneficial intestinal flora and the immune system, and produces no adverse symptoms. If however, the immune system or the balance of flora are compromised, C. albicans can produce serious symptoms. C. albicans adheres to the oral mucosa and GI tract to cause colonization, and the GI tract is often the portal of entry for many forms of disseminated infection. Factors that affect adherence are very important in pathogenesis. Mucotaneous infections are divided into oropharyngeal candidiasis (thrush), esophageal candidiasis, GI candidiasis, and vaginal candidiasis.
Chronic Candida albicans infections typically cause genitourinary complaints (menstrual disorders, vaginitis, colitis, gastritis, cystitis) allergic responses (acne, hay fever, asthma, ear aches, hypersensitivity to chemicals or foods, bronchitis), and/or nervous disorders (depression, memory lapses and inability to concentrate).
- Doctors estimate that approximately 75% of all women will experience at least one symptomatic yeast infection during their lifetime. Risk factors for disseminated disease include prior therapy with antibiotics, recent surgery, indwelling IV or urinary catheters, extensive burns, concomitant bacterial infections, and administrations of total parenteral nutrition (TPN). Dissemination of C. albicans can result in infections in single or multiple organs including the eye, brain, heart, kidney, skin, bone, and joints.
Oral candidiasis is generally not considered life threatening, however, it causes discomfort, and in immuno-compromised patients, can spread to the esophagus, causing ulcerations and mucosal perforation. A variety of local and systemic factors are generally necessary for the development of oral candidiasis. Precipitating factors include age, presence of host immune deficiencies (including malignancies, diabetes mellitus and AIDS), nutritional deficiencies, radiation therapy, antineoplastic agents, and use of local or systemic antibiotics or corticosteroids. Oral candidiasis occurs in as many as 5% of newborn infants, greater than 35% of patients with leukemia of those receiving chemotherapy for solid tumors, patients undergoing organ transplantation, and approximately 10% of all hospitalized, debilitated, elderly patients. Vaginal candidiasis occurs in approximately one fourth of women in their childbearing years. Factors thought to predispose infections include the use of oral contraceptives, pregnancy, obesity, diabetes, drug therapy with systemic corticosteroids, antineoplastic agents, and systemic antibiotics.
Within the urinary tract, the most commonly found type of lesions are Candida cystitis that often follows therapy with broad spectrum antibiotics or urinary catheterization, or renal abscesses from hematogenous dissemination. It is generally asymptomatic and clears spontaneously without the use of antifungal agents. Diagnosis is often difficult due to normal colonization of Candida.
The Role of Fatty Acids The antifungal properties of certain fatty acids has been recognized for many years. This activity appears to be related to an ability to reversibly react with cellular membranes and alter membrane permeability. These fatty acids inhibit C. albicans ability to form fungal rhizoids that can penetrate the intestinal mucosa, spreading toxins and intestinal substances throughout the body.
Caprylic Acid Caprylic acid is a mycostatic agent. This 8-carbon fatty acid is commonly found in foods such as coconut milk and milk fat. It helps maintain normal bacterial flora in the gastrointestinal tract. Studies have reported that dietary caprylic acid helps inhibit the growth of C. albicans and other opportunistic fungi in both the small and large intestine (Neuhauser-1954). At the same time, caprylic acid does not seem to adversely affect the growth of beneficial intestinal microflora. Caprylic has been shown to be safe and effective with no reports of interference with medications, and no significant side effects have been reported.
Propionic Acid Propionic acid is known for its antifungal properties. Propionates inhibit pathnogenic fungi and can help in the management of candidiasis by preventing the conversion to candida to its pathnogenic fungal form.
Sorbic Acid Sorbic acid is an effective antimycotic agent which demonstrates broad spectrum activity against yeast and fungal molds. Sorbic acid is less active against bacteria, and can aid in the normalization of gastrointestinal flora by reducing candida overgrowth.
Biotin Biotin is a water soluble B vitamin which is essential for the activity of many important metabolic reactions. It is important in maintaining healthy skin, hair, sweat glands, nerves and bone marrow. Biotin is a cofactor in four key carboxylase enzymes, with primary activity in the mitochondria. Its activity is required for normal neuronal and hematopoietic function. C. albicans require a biotin deficiency to convert into its invasive fungal form. Researchers have found that high levels of biotin supplementation can prevent this conversion.
Directions for Use: As a dietary supplement for adults and children 12 or more years of age, take one or two capsules twice daily, or as directed by a qualified healthcare professional.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
References - Roberts JA. Management of pyelonephritis and upper urinary tract infections. Urol Clin North Am. Nov 1999;26(4):753-63. - Bland, Jeff, Candida albicans: an unsuspected problem, Linus Paulin Institute, Palo Alto, Ca 1984. - Wyss, O. et al., The Fungistatic and Fungicidal action of fatty acids and related compounds, ARCH. Biochem., 7,415 1945. - Sorbic Acids and its Salts, Handbook of food additives; CRC Press, Cleveland, OH pg. 129-133 1972. - Hoffman, C., et al., Food Research, 4, 539-545 1939. - IntraMedicine Monograph - Candidiasis.