COX Free Sustained Release
Growing Numbers. Today it is estimated that over 40 million people have some form of arthritis, and that by the year 2020, the number will hit 60 million. Due to the fact that arthritis is a progressive disease, when you add to these figures the number of people who are not yet diagnosed, or who are suffering the early stages of joint pain, the totals are staggering.
Pain and Inflammation. Joint pain usually occurs when cartilage, the slippery, lubricated cushion between bones, deteriorates. This can be the result of an earlier injury, because it is genetically weak or due to the process of aging. The result is a painful grinding of bone against bone. When analgesics aren’t helpful, pain-relieving Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) are used. NSAIDs work by inhibiting an enzyme called cyclo-oxygenase (or COX). Inhibiting COX decreases the production of prostaglandins, the principal directors of pain and inflammation. There are two COX molecules. COX-1, found in most body tissues, is an enzyme that produces chemical messengers that direct important functions in the body, like the formation of a protective lining in the digestive tract. However, in the presence of inflammation, different messengers are formed. These are called COX-2 enzymes, and can promote pain and inflammation. The problem with most NSAIDs is that while they can inhibit COX-2 and ease pain and inflammation in our joints, they can also inhibit COX-1, leaving the lining of our Gastrointestinal tract vulnerable to ulcers and bleeding.
Vinco’s COX Free The ingredients in Vinco’s COX Free have been shown to down regulate the inflammatory pathway for healthy COX II inhibition. It provides contemporary ingredients at full therapeutic doses, giving you a fresh approach for full system support.
Ginger (Zingiber officinale) The antiemetic activity of ginger is believed to be due to shagol, while gingerol has been shown to stimulate gastric secretions and peristalsis. Ginger may be warranted instead of antihistamines for motion sickness because it does not cause drowsiness. The volatile oils in ginger are thought to act as peripheral vaso dilators or circulatory stimulants. Ginger’s structural phenols are similar to aspirin and may have an effect on prostaglandins, PGE2 and PGF2, as well as thromboxane, leading to its use as an anticoagulant.
Turmeric (Curcuma langa) Turmeric has been reported to be a potent anti-inflammatory and antioxidant which may be of value in the treatment of rheumatic disorders. The antiinflammatory activity has been claimed to be comparable to NSAIDs, producing significant improvement in clinical trials involving individuals with rheumatoid arthritis.
Boswellia (Boswellia serrata) Boswellia’s constituents, termed boswellic acids, have an anti-inflammatory action. Reports suggest that boswellia is effective in the management of arthritis. Boswellia inhibits pro-inflammatory mediators in the body, such as leukotrienes. As opposed to NSAIDs, long-term use of Boswellia does not lead to irritation or ulceration of the stomach.
Methyl Sulfonyl Methane (MSM) MSM is derived from DMSO. DMSO, or Dimethyl Sulfoxide, is claimed to be an anti-inflammatory agent. MSM is a source of biological sulfur, an important component of proteins, connective tissues, hormones and enzymes. MSM is believed to relieve pain by several possible mechanisms. It may inhibit transmission of pain impulses along type C nerve fibers, increase blood flow and reduce muscular spasm. In addition, MSM appears to act as an anti-inflammatory agent, possibly by limiting the release of inflammatory mediators.
Collagen (Type II) Type II collagen is the primary form of collagen contained in cartilage. Type II collagen extracts contain the amino acids found in the framework of human cartilage and can support the production of collagen in the body. These extracts reportedly aid in reducing the destruction of collagen within the body by "giving themselves up" in times of trauma. They also may provide anti-inflammatory activity and may improve joint flexibility.
Licorice (Glycyrrhiza glabra) Although licorice is most recognized as a flavoring agent, it has a long history as a medicinal herb. It has been used to relieve symptoms in individuals with adrenal insufficiency and as a treatment for upper respiratory symptoms. DGL licorice may be beneficial in a variety of gastrointestinal disorders, particularly in peptic ulcer disease and inflammatory disorders. Licorice also is reported to inhibit prostaglandin and leukotriene synthesis.
Signs of Joint Inflammation: • Swelling • Stiffness • Tenderness • Redness or warmth May be accompanied with: • Weight Loss • Fever • Weakness
Pain is the body’s message that something is wrong in the system. These issues of pain are not diseases of themselves, but are symptoms of a dysfunction in associated structures. An aging joint shows evidence of wear, leading to pain. If the condition is not treated, the joint can become immobile and this may ultimately lead to deformity of the joint. While aging can not be stopped, the pain and inflammation that result from such trauma can be managed.
Directions for Use: As a dietary supplement for adults and children 12 or more years of age, take one tablet two or three times daily, or as directed by a qualified healthcare professional.
Supplement Facts Serving Size: 2 Sustained Release Tablets Servings per Container: 30
Amount per Serving %DV
Ginger Root Std. Extract (5% Gingerols) 100 mg * Turmeric Rhizome Std. Extract (95% Curcuminoids) 300 mg * Boswellia Serrata Gum Resin (40% Boswellic Acid) 200 mg * DL-Phenylalanine 500 mg * Methyl-Sulfonyl-Methane (MSM) 500 mg * Collagen (Type II) 100 mg * DGL Licorice Root 200 mg * * Daily Value (DV) not established DV is based on a 2,000 calorie diet Other Ingredients: Dicalcium Phosphate, Stearic Acid, Silicon Dioxide, Modified Cellulose Gum.