Maximizing The Methylation Cycle
The Methylation Cycle is an important biochemical pathwaythat regulates a wide range of crucial bodily functions, including:
Maintaining DNA Integrity
Maintaining a balanced inflammatory response
Methylation is involved in almost every biochemical processin the body. Promoting optimal methylation through better nutrition is avital part of maintaining health and protecting cellular function.
Methyl CpG provides targeted amounts of 5-MTHF,methylcobalamin (Vitamin B12), Vitamin B6, Riboflavin, and Trimethyl Glycine allin one capsule to aggressively support the primary pathways of methylation andmaintain homocysteine balance.
Folate: Adequate folate status is critical for maintaining optimal methylation. Folate is essential for DNA and RNA synthesis, neurotransmitter synthesis, and the conversion of homocysteine to methionine, thus supporting healthy homocysteine levels. Methyl CpG has an aggressive 2mg-dose of 5-Methyltetrahydrofolate per capsule, giving your patients the intensive support they need to maximize the methylation cycle.
Vitamin B12: B12 is considered by many to be the second most important nutrient in balancing homocysteine levels. It is a required co-factor in the conversion of homocysteine to methionine via the folate pathway. Vitamin B12 shortfall is common in the elderly and those consuming vegetarian diets.
Vitamin B6: Another important ingredient for methylation and homocysteine metabolism, Vitamin B6 is known to maintain balanced homocysteine levels, even amongst those who have previously supplemented folate alone.
Riboflavin: Riboflavin has a positive effect on homocysteine metabolism and methylation. Recent studies show that plasma homocysteine is inversely related to riboflavin in subjects with the 677C>T polymorphism. This indicates the importance of riboflavin status for those who have impaired methylation due to 677C>T polymorphisms.
Betaine (Trimethyl glycine): Betaine (TMG) acts as a strong methyl donor to homocysteine—converting it to methionine. This conversion pathway occurs in the liver and kidney and contributes to optimal homocysteine balance in those patients with impaired methionine metabolism.